Humoral immunity to human metapneumovirus infection in adults
نویسندگان
چکیده
منابع مشابه
humoral immunity to human neoplasms
using complement fixation technique, serial serum samples from 15 patients undergoing surgical removal of malignant tumors were assayed for the presence of tumors antibodies against the cellular fractions of both normal and carcinomatous tissue. antibody responses against tumor associated antigens were detected in four cases. in all cases antibody activity was directed only against the supernat...
متن کاملHuman Metapneumovirus in Adults
Human metapneumovirus (HMPV) is a relative newly described virus. It was first isolated in 2001 and currently appears to be one of the most significant and common human viral infections. Retrospective serologic studies demonstrated the presence of HMPV antibodies in humans more than 50 years earlier. Although the virus was primarily known as causative agent of respiratory tract infections in ch...
متن کاملExperimental infection of adults with recombinant wild-type human metapneumovirus.
BACKGROUND Human metapneumovirus (HMPV) causes lower respiratory tract infections in young children. rHMPV-SHs is a recombinant HMPV (rHMPV) based on a biologically derived wild-type HMPV strain. We characterized its infectivity and immunogenicity in healthy adults to determine whether it would be suitable for use as the parent virus for the development of live attenuated rHMPV vaccines. METH...
متن کاملSerosurvey of human metapneumovirus infection in Croatia.
AIM To assess the seroprevalence of human metapneumovirus (hMPV) in Croatia. METHODS During 2005, a total of 137 serum specimens from Croatian patients aged from 6 days to 51 years, without respiratory symptoms, were collected at the Croatian National Institute of Public Health. The sera were examined using the indirect immunofluorescent assay. RESULTS The overall hMPV seropositivity rate i...
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detection of chikungunya virus using a RT-PCR/nested PCR combination .opment of a TaqMan RT-PCR assay without RNA extraction step for the detection and quantifi cation of African chikungunya viruses. To the Editor: Respiratory viral infections can be associated with a wide range of clinical manifestations from self-limiting upper respiratory tract diseases to pneumonia (1). However, in general,...
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ژورنال
عنوان ژورنال: Vaccine
سال: 2010
ISSN: 0264-410X
DOI: 10.1016/j.vaccine.2009.11.063